Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase

Binary systems based on site-specific recombination have been used for tumor specific transcription targeting of suicide genes in animal models. In these binary systems a site specific recombinase or integrase that is expressed from a tumor specific promoter drives tumor specific expression of a cyt...

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Detalles Bibliográficos
Autores principales: Elias, Amer, Spector, Itay, Sogolovsky-Bard, Ilana, Gritsenko, Natalia, Rask, Lene, Mainbakh, Yuli, Zilberstein, Yael, Yagil, Ezra, Kolot, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846993/
https://www.ncbi.nlm.nih.gov/pubmed/27117628
http://dx.doi.org/10.1038/srep24971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846993/
https://www.ncbi.nlm.nih.gov/pubmed/27117628
http://dx.doi.org/10.1038/srep24971

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