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Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase
Binary systems based on site-specific recombination have been used for tumor specific transcription targeting of suicide genes in animal models. In these binary systems a site specific recombinase or integrase that is expressed from a tumor specific promoter drives tumor specific expression of a cyt...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846993/ https://www.ncbi.nlm.nih.gov/pubmed/27117628 http://dx.doi.org/10.1038/srep24971 |