Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer’s disease

Sphingosine 1-phosphate (SP1) receptors may be attractive targets for modulation of inflammatory processes in neurodegenerative diseases. Recently fingolimod, a functional S1P1 receptor antagonist, was introduced for treatment of multiple sclerosis. We postulated that anti-inflammatory mechanisms of...

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Detalles Bibliográficos
Autores principales: Aytan, Nurgul, Choi, Ji-Kyung, Carreras, Isabel, Brinkmann, Volker, Kowall, Neil W., Jenkins, Bruce G., Dedeoglu, Alpaslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847010/
https://www.ncbi.nlm.nih.gov/pubmed/27117087
http://dx.doi.org/10.1038/srep24939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847010/
https://www.ncbi.nlm.nih.gov/pubmed/27117087
http://dx.doi.org/10.1038/srep24939

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