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Development of camelid single chain antibodies against Shiga toxin type 2 (Stx2) with therapeutic potential against Hemolytic Uremic Syndrome (HUS)

Shiga toxin (Stx)-producing Escherichia coli (STEC) infections are implicated in the development of the life-threatening Hemolytic Uremic Syndrome (HUS). Despite the magnitude of the social and economic problems caused by STEC infections, no licensed vaccine or effective therapy is presently availab...

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Detalles Bibliográficos
Autores principales: Mejías, Maria P., Hiriart, Yanina, Lauché, Constanza, Fernández-Brando, Romina J., Pardo, Romina, Bruballa, Andrea, Ramos, María V., Goldbaum, Fernando A., Palermo, Marina S., Zylberman, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847011/
https://www.ncbi.nlm.nih.gov/pubmed/27118524
http://dx.doi.org/10.1038/srep24913