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Pronounced peptide selectivity for melanoma through tryptophan end-tagging

Effects of oligotryptophan end-tagging on the uptake of arginine-rich peptides into melanoma cells was investigated under various conditions and compared to that into non-malignant keratinocytes, fibroblasts, and erythrocytes, also monitoring resulting cell toxicity. In parallel, biophysical studies...

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Detalles Bibliográficos
Autores principales: Duong, Dinh Thuy, Singh, Shalini, Bagheri, Mojtaba, Verma, Navin Kumar, Schmidtchen, Artur, Malmsten, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847013/
https://www.ncbi.nlm.nih.gov/pubmed/27117225
http://dx.doi.org/10.1038/srep24952