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Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase
Type I modular polyketide synthases (PKSs) produce polyketide natural products by passing a growing acyl substrate chain between a series of enzyme domains housed within a gigantic multifunctional polypeptide assembly. Throughout each round of chain extension and modification reactions, the substrat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847154/ https://www.ncbi.nlm.nih.gov/pubmed/26920023 http://dx.doi.org/10.1042/BCJ20160041 |