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Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase

Type I modular polyketide synthases (PKSs) produce polyketide natural products by passing a growing acyl substrate chain between a series of enzyme domains housed within a gigantic multifunctional polypeptide assembly. Throughout each round of chain extension and modification reactions, the substrat...

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Detalles Bibliográficos
Autores principales:	Vance, Steven, Tkachenko, Olga, Thomas, Ben, Bassuni, Mona, Hong, Hui, Nietlispach, Daniel, Broadhurst, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847154/ https://www.ncbi.nlm.nih.gov/pubmed/26920023 http://dx.doi.org/10.1042/BCJ20160041

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