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Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore

Iron is essential for the survival and virulence of pathogenic bacteria. The FeoB transporter allows the bacterial cell to acquire ferrous iron from its environment, making it an excellent drug target in intractable pathogens. The protein consists of an N-terminal GTP-binding domain and a C-terminal...

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Detalles Bibliográficos
Autores principales: Seyedmohammad, Saeed, Fuentealba, Natalia Alveal, Marriott, Robert A.J., Goetze, Tom A., Edwardson, J. Michael, Barrera, Nelson P., Venter, Henrietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847171/
https://www.ncbi.nlm.nih.gov/pubmed/26934982
http://dx.doi.org/10.1042/BSR20160046