Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways

Reactive oxygen species (ROS)-triggered cardiac cell injury is recognized as the major contributor for the pathogenesis progression of ischaemic cardiovascular diseases. Sulfiredoxin-1 (Srx-1) is an endogenous antioxidant and exerts the crucial neuroprotective effects in cerebral ischaemia. However,...

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Detalles Bibliográficos
Autores principales: Zhang, Jiankai, He, Zhangyou, Guo, Jinhua, Li, Zhe, Wang, Xiaohong, Yang, Chun, Cui, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847177/
https://www.ncbi.nlm.nih.gov/pubmed/26992405
http://dx.doi.org/10.1042/BSR20160076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847177/
https://www.ncbi.nlm.nih.gov/pubmed/26992405
http://dx.doi.org/10.1042/BSR20160076

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