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Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet

BACKGROUND: Obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD) are serious health concerns, especially in Western populations. Antibiotic exposure and high-fat diet (HFD) are important and modifiable factors that may contribute to these diseases. METHODS: To investigate the rela...

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Detalles Bibliográficos
Autores principales: Mahana, Douglas, Trent, Chad M., Kurtz, Zachary D., Bokulich, Nicholas A., Battaglia, Thomas, Chung, Jennifer, Müller, Christian L., Li, Huilin, Bonneau, Richard A., Blaser, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847194/
https://www.ncbi.nlm.nih.gov/pubmed/27124954
http://dx.doi.org/10.1186/s13073-016-0297-9