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Role of transient receptor potential ankyrin 1 channels in Alzheimer’s disease

BACKGROUND: Transient receptor potential ankyrin 1 (TRPA1) channel plays an important role in pain and inflammation. However, little is known about the significance of the TRPA1 channel in the pathophysiology of Alzheimer’s disease (AD). METHODS: Wild-type (WT), TRPA1(−/−), amyloid precursor protein...

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Detalles Bibliográficos
Autores principales: Lee, Kuan-I, Lee, Hsueh-Te, Lin, Hui-Ching, Tsay, Huey-Jen, Tsai, Feng-Chuan, Shyue, Song-Kun, Lee, Tzong-Shyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847235/
https://www.ncbi.nlm.nih.gov/pubmed/27121378
http://dx.doi.org/10.1186/s12974-016-0557-z