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U1-RNP and Toll-like receptors in the pathogenesis of mixed connective tissue disease Part II. Endosomal TLRs and their biological significance in the pathogenesis of mixed connective tissue disease
Mixed connective tissue disease (MCTD) is a chronic autoimmune immunopathological disease of unknown etiology, which is characterized by the presence of various clinical symptoms and the presence of autoantibodies against U1-RNP particles. The U1-RNP component engages immune cells and their receptor...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847297/ https://www.ncbi.nlm.nih.gov/pubmed/27407241 http://dx.doi.org/10.5114/reum.2015.53136 |