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Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent

INTRODUCTION: Cannabinoid compounds, both nonspecific as well as agonists selective for either cannabinoid receptor 1 (CB(1)) or cannabinoid receptor 2 (CB(2)), have been shown to modulate the tumor microenvironment by inducing apoptosis in tumor cells in several model systems. The mechanism of this...

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Detalles Bibliográficos
Autores principales: Hanlon, Katherine E, Lozano-Ondoua, Alysia N, Umaretiya, Puja J, Symons-Liguori, Ashley M, Chandramouli, Anupama, Moy, Jamie K, Kwass, William K, Mantyh, Patrick W, Nelson, Mark A, Vanderah, Todd W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847606/
https://www.ncbi.nlm.nih.gov/pubmed/27186076
http://dx.doi.org/10.2147/BCTT.S100393