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Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory decline and subsequent loss of broader cognitive functions(1). Memory decline in early stages of Alzheimer’s is mostly limited to episodic memory, for which the hippocampus (HPC) plays a crucial role(2). How...

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Detalles Bibliográficos
Autores principales: Roy, Dheeraj S., Arons, Autumn, Mitchell, Teryn I., Pignatelli, Michele, Ryan, Tomás J., Tonegawa, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847731/
https://www.ncbi.nlm.nih.gov/pubmed/26982728
http://dx.doi.org/10.1038/nature17172