Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae

Nonsense mutations generate in-frame stop codons in mRNA leading to a premature arrest of translation. Functional consequences of premature termination codons (PTCs) include the synthesis of truncated proteins with loss of protein function causing severe inherited or acquired diseases. A therapeutic...

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Detalles Bibliográficos
Autores principales: Altamura, Emiliano, Borgatti, Monica, Finotti, Alessia, Gasparello, Jessica, Gambari, Roberto, Spinelli, Mariangela, Castaldo, Rosa, Altamura, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847774/
https://www.ncbi.nlm.nih.gov/pubmed/27119736
http://dx.doi.org/10.1371/journal.pone.0154260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847774/
https://www.ncbi.nlm.nih.gov/pubmed/27119736
http://dx.doi.org/10.1371/journal.pone.0154260

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