Rosuvastatin Attenuates CD40L-Induced Downregulation of Extracellular Matrix Production in Human Aortic Smooth Muscle Cells via TRAF6-JNK-NF-κB Pathway

CD40L and statins exhibit pro-inflammatory and anti-inflammatory effects, respectively. They are both pleiotropic and can regulate extracellular matrix (ECM) degeneration in an atherosclerotic plaque. Statins can decrease both the CD40 expression and the resulting inflammation. However, the effects...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Lin, Zhou, Yuan-Li, Sun, Wei, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847831/
https://www.ncbi.nlm.nih.gov/pubmed/27120457
http://dx.doi.org/10.1371/journal.pone.0153919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847831/
https://www.ncbi.nlm.nih.gov/pubmed/27120457
http://dx.doi.org/10.1371/journal.pone.0153919

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