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TNFα/IFNγ Mediated Intestinal Epithelial Barrier Dysfunction Is Attenuated by MicroRNA-93 Downregulation of PTK6 in Mouse Colonic Epithelial Cells

Since inflammatory bowel diseases (IBD) represent significant morbidity and mortality in the US, the need for defining novel drug targets and inflammatory mechanisms would be of considerable benefit. Although protein tyrosine kinase 6 (PTK6, also known as breast tumor kinase BRK) has been primarily...

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Detalles Bibliográficos
Autores principales: Haines, Ricci J., Beard, Richard S., Eitner, Rebecca A., Chen, Liwei, Wu, Mack H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847919/
https://www.ncbi.nlm.nih.gov/pubmed/27119373
http://dx.doi.org/10.1371/journal.pone.0154351