Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma

Compound EGFR mutations, defined as double or multiple mutations in the EGFR tyrosine kinase domain, are frequently detected with advances in sequencing technology but its clinical significance is unclear. This study analyzed 61 cases of EGFR mutation positive lung adenocarcinoma using next-generati...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Cho, Eun Na, Park, Heae Surng, Hong, Ji Young, Lim, Seri, Youn, Jong Pil, Hwang, Seung Yong, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848002/
https://www.ncbi.nlm.nih.gov/pubmed/26785607
http://dx.doi.org/10.1080/15384047.2016.1139235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848002/
https://www.ncbi.nlm.nih.gov/pubmed/26785607
http://dx.doi.org/10.1080/15384047.2016.1139235

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