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Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma
Compound EGFR mutations, defined as double or multiple mutations in the EGFR tyrosine kinase domain, are frequently detected with advances in sequencing technology but its clinical significance is unclear. This study analyzed 61 cases of EGFR mutation positive lung adenocarcinoma using next-generati...
Autores principales: | Kim, Eun Young, Cho, Eun Na, Park, Heae Surng, Hong, Ji Young, Lim, Seri, Youn, Jong Pil, Hwang, Seung Yong, Chang, Yoon Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848002/ https://www.ncbi.nlm.nih.gov/pubmed/26785607 http://dx.doi.org/10.1080/15384047.2016.1139235 |
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