A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter

Cellular immunity against viral infection and tumor cells depends on antigen presentation by the major histocompatibility complex class 1 molecules (MHC I). Intracellular antigenic peptides are transported into the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP...

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Detalles Bibliográficos
Autores principales: Oldham, Michael L., Hite, Richard K., Steffen, Alanna M., Damko, Ermelinda, Li, Zongli, Walz, Thomas, Chen, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848044/
https://www.ncbi.nlm.nih.gov/pubmed/26789246
http://dx.doi.org/10.1038/nature16506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848044/
https://www.ncbi.nlm.nih.gov/pubmed/26789246
http://dx.doi.org/10.1038/nature16506

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