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A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter
Cellular immunity against viral infection and tumor cells depends on antigen presentation by the major histocompatibility complex class 1 molecules (MHC I). Intracellular antigenic peptides are transported into the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP...
Autores principales: | Oldham, Michael L., Hite, Richard K., Steffen, Alanna M., Damko, Ermelinda, Li, Zongli, Walz, Thomas, Chen, Jue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848044/ https://www.ncbi.nlm.nih.gov/pubmed/26789246 http://dx.doi.org/10.1038/nature16506 |
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