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Proline-based Phosphoramidite Reagents for the Reductive Ligation of S-Nitrosothiols
S-Nitrosothiols have many biological implications but are rarely used in organic synthesis. In this work we report the development of proline-based phosphoramidite substrates that can effectively convert S-nitrosothiols to proline-based sulfenamides through a reductive ligation process. A unique pro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848125/ https://www.ncbi.nlm.nih.gov/pubmed/26758493 http://dx.doi.org/10.1038/ja.2015.144 |