Cis-regulatory architecture of a brain-signaling center predates the origin of chordates

Genomic approaches have predicted hundreds of thousands of tissue specific cis-regulatory sequences, but the determinants critical to their function and evolutionary history are mostly unknown(1–4). Here, we systematically decode a set of brain enhancers active in the zona limitans intrathalamica (z...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Minor, Paul J., Zhao, Ying-Tao, Jeong, Yongsu, Pani, Ariel M., King, Anna N., Symmons, Orsolya, Gan, Lin, Cardoso, Wellington V., Spitz, François, Lowe, Christopher J., Epstein, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848136/
https://www.ncbi.nlm.nih.gov/pubmed/27064252
http://dx.doi.org/10.1038/ng.3542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848136/
https://www.ncbi.nlm.nih.gov/pubmed/27064252
http://dx.doi.org/10.1038/ng.3542

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