Computational discovery of transcription factors associated with drug response

This study integrates gene expression, genotype and drug response data in lymphoblastoid cell lines with transcription factor (TF)-binding sites from ENCODE (Encyclopedia of Genomic Elements) in a novel methodology that elucidates regulatory contexts associated with cytotoxicity. The method, GENMi (...

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Detalles Bibliográficos
Autores principales: Hanson, C, Cairns, J, Wang, L, Sinha, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848185/
https://www.ncbi.nlm.nih.gov/pubmed/26503816
http://dx.doi.org/10.1038/tpj.2015.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848185/
https://www.ncbi.nlm.nih.gov/pubmed/26503816
http://dx.doi.org/10.1038/tpj.2015.74

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