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Computational discovery of transcription factors associated with drug response
This study integrates gene expression, genotype and drug response data in lymphoblastoid cell lines with transcription factor (TF)-binding sites from ENCODE (Encyclopedia of Genomic Elements) in a novel methodology that elucidates regulatory contexts associated with cytotoxicity. The method, GENMi (...
Autores principales: | Hanson, C, Cairns, J, Wang, L, Sinha, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848185/ https://www.ncbi.nlm.nih.gov/pubmed/26503816 http://dx.doi.org/10.1038/tpj.2015.74 |
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