Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis

Nutrient overload and genetic factors have led to a worldwide epidemic of obesity that is the underlying cause of diabetes, atherosclerosis, and cardiovascular disease. In this study, we used macrolide drugs such as FK506, rapamycin, and macrolide derived, timcodar (VX-853), to determine their effec...

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Detalles Bibliográficos
Autores principales: Hinds, Terry D., John, Kezia, McBeth, Lucien, Trabbic, Christopher J., Sanchez, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848453/
https://www.ncbi.nlm.nih.gov/pubmed/27190501
http://dx.doi.org/10.1155/2016/6218637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848453/
https://www.ncbi.nlm.nih.gov/pubmed/27190501
http://dx.doi.org/10.1155/2016/6218637

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