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The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

The intimate link between location of fat accumulation and metabolic disease risk and depot-specific differences is well established, but how these differences between depots are regulated at the molecular level remains largely unclear. Here we show that TRIP-Br2 mediates endoplasmic reticulum (ER)...

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Detalles Bibliográficos
Autores principales: Qiang, Guifen, Kong, Hyerim Whang, Fang, Difeng, McCann, Maximilian, Yang, Xiuying, Du, Guanhua, Blüher, Matthias, Zhu, Jinfang, Liew, Chong Wee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848483/
https://www.ncbi.nlm.nih.gov/pubmed/27109496
http://dx.doi.org/10.1038/ncomms11378