A novel type 2 diabetes risk allele increases the promoter activity of the muscle-specific small ankyrin 1 gene

Genome-wide association studies have identified Ankyrin-1 (ANK1) as a common type 2 diabetes (T2D) susceptibility locus. However, the underlying causal variants and functional mechanisms remain unknown. We screened for 8 tag single nucleotide polymorphisms (SNPs) in ANK1 between 2 case-control studi...

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Detalles Bibliográficos
Autores principales: Yan, Rengna, Lai, Shanshan, Yang, Yang, Shi, Hongfei, Cai, Zhenming, Sorrentino, Vincenzo, Du, Hong, Chen, Huimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848520/
https://www.ncbi.nlm.nih.gov/pubmed/27121283
http://dx.doi.org/10.1038/srep25105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848520/
https://www.ncbi.nlm.nih.gov/pubmed/27121283
http://dx.doi.org/10.1038/srep25105

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