GPR40 agonist ameliorates liver X receptor-induced lipid accumulation in liver by activating AMPK pathway

Hepatic steatosis is strongly linked to insulin resistance and type 2 diabetes. GPR40 is a G protein-coupled receptor mediating free fatty acid-induced insulin secretion and thus plays a beneficial role in the improvement of diabetes. However, the impact of GPR40 agonist on hepatic steatosis still r...

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Detalles Bibliográficos
Autores principales: Li, Meng, Meng, Xiangyu, Xu, Jie, Huang, Xiuqing, Li, Hongxia, Li, Guoping, Wang, Shu, Man, Yong, Tang, Weiqing, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848522/
https://www.ncbi.nlm.nih.gov/pubmed/27121981
http://dx.doi.org/10.1038/srep25237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848522/
https://www.ncbi.nlm.nih.gov/pubmed/27121981
http://dx.doi.org/10.1038/srep25237

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