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GPR40 agonist ameliorates liver X receptor-induced lipid accumulation in liver by activating AMPK pathway
Hepatic steatosis is strongly linked to insulin resistance and type 2 diabetes. GPR40 is a G protein-coupled receptor mediating free fatty acid-induced insulin secretion and thus plays a beneficial role in the improvement of diabetes. However, the impact of GPR40 agonist on hepatic steatosis still r...
Autores principales: | Li, Meng, Meng, Xiangyu, Xu, Jie, Huang, Xiuqing, Li, Hongxia, Li, Guoping, Wang, Shu, Man, Yong, Tang, Weiqing, Li, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848522/ https://www.ncbi.nlm.nih.gov/pubmed/27121981 http://dx.doi.org/10.1038/srep25237 |
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