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The structural basis of chicken, swine and bovine CD8αα dimers provides insight into the co-evolution with MHC I in endotherm species

It is unclear how the pivotal molecules of the adaptive immune system (AIS) maintain their inherent characteristics and relationships with their co-receptors over the course of co-evolution. CD8α, a fundamental but simple AIS component with only one immunoglobulin variable (IgV) domain, is a good ex...

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Detalles Bibliográficos
Autores principales: Liu, Yanjie, Li, Xin, Qi, Jianxun, Zhang, Nianzhi, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848529/
https://www.ncbi.nlm.nih.gov/pubmed/27122108
http://dx.doi.org/10.1038/srep24788