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Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade

Statins are used widely to lower serum cholesterol and the incidence of cardiovascular diseases. Growing evidence shows that statins also exhibit beneficial effects against cancers. In this study, we investigated the molecular mechanisms involved in lovastatin-induced cell death in Fadu hypopharynge...

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Detalles Bibliográficos
Autores principales: Yen, Chia-Sheng, Chen, Jung-Chien, Chang, Yi-Fang, Hsu, Ya-Fen, Chiu, Pei-Ting, Shiue, Ching, Chuang, Yu-Fan, Ou, George, Hsu, Ming-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848532/
https://www.ncbi.nlm.nih.gov/pubmed/27122225
http://dx.doi.org/10.1038/srep25082