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Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade
Statins are used widely to lower serum cholesterol and the incidence of cardiovascular diseases. Growing evidence shows that statins also exhibit beneficial effects against cancers. In this study, we investigated the molecular mechanisms involved in lovastatin-induced cell death in Fadu hypopharynge...
Autores principales: | Yen, Chia-Sheng, Chen, Jung-Chien, Chang, Yi-Fang, Hsu, Ya-Fen, Chiu, Pei-Ting, Shiue, Ching, Chuang, Yu-Fan, Ou, George, Hsu, Ming-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848532/ https://www.ncbi.nlm.nih.gov/pubmed/27122225 http://dx.doi.org/10.1038/srep25082 |
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