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Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer

Although early detection and treatment of prostate cancer (PCa) improves outcomes, many patients still die of metastatic PCa. Here, we report that metastatic PCa exhibits reduced levels of the microRNAsmiR-101 and miR-27a. These micro-RNAs (miRNAs) negatively regulate cell invasion and inhibit the e...

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Detalles Bibliográficos
Autores principales: Lin, Shih-Chieh, Kao, Chung-Yang, Lee, Hui-Ju, Creighton, Chad J., Ittmann, Michael M., Tsai, Shaw-Jenq, Tsai, Sophia Y., Tsai, Ming-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848536/
https://www.ncbi.nlm.nih.gov/pubmed/27108958
http://dx.doi.org/10.1038/ncomms11418