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Quantification of dopaminergic neuron differentiation and neurotoxicity via a genetic reporter

Human pluripotent stem cells provide a powerful human-genome based system for modeling human diseases in vitro and for potentially identifying novel treatments. Directed differentiation of pluripotent stem cells produces many specific cell types including dopaminergic neurons. Here, we generated a g...

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Detalles Bibliográficos
Autores principales: Cui, Jun, Rothstein, Megan, Bennett, Theo, Zhang, Pengbo, Xia, Ninuo, Reijo Pera, Renee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848568/
https://www.ncbi.nlm.nih.gov/pubmed/27121904
http://dx.doi.org/10.1038/srep25181