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Long-chain unsaturated fatty acids reduce the transcriptional activity of the rat follicle-stimulating hormone β-subunit gene

Here, we assessed the effects of long-chain fatty acids (LCFAs) and the LCFA receptor agonist GW9508 on the transcription of the gonadotropin subunit genes Cga, Lhb and Fshb because LCFA receptor GPR120 was observed in mouse gonadotropes in our recent study. A transcription assay using LβT2 cells de...

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Detalles Bibliográficos
Autores principales: MORIYAMA, Ryutaro, YAMAZAKI, Tsubasa, KATO, Takako, KATO, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848577/
https://www.ncbi.nlm.nih.gov/pubmed/26853521
http://dx.doi.org/10.1262/jrd.2015-138