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Intranasal Immunization with Influenza Virus-Like Particles Containing Membrane-Anchored Cholera Toxin B or Ricin Toxin B Enhances Adaptive Immune Responses and Protection against an Antigenically Distinct Virus

Vaccination is the most effective means to prevent influenza virus infection, although current approaches are associated with suboptimal efficacy. Here, we generated virus-like particles (VLPs) composed of the hemagglutinin (HA), neuraminidase (NA) and matrix protein (M1) of A/Changchun/01/2009 (H1N...

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Detalles Bibliográficos
Autores principales: Ji, Xianliang, Ren, Zhiguang, Xu, Na, Meng, Lingnan, Yu, Zhijun, Feng, Na, Sang, Xiaoyu, Li, Shengnan, Li, Yuanguo, Wang, Tiecheng, Zhao, Yongkun, Wang, Hualei, Zheng, Xuexing, Jin, Hongli, Li, Nan, Yang, Songtao, Cao, Jinshan, Liu, Wensen, Gao, Yuwei, Xia, Xianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848608/
https://www.ncbi.nlm.nih.gov/pubmed/27110810
http://dx.doi.org/10.3390/v8040115