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HIV-1 Mutation and Recombination Rates Are Different in Macrophages and T-cells

High rates of mutation and recombination help human immunodeficiency virus (HIV) to evade the immune system and develop resistance to antiretroviral therapy. Macrophages and T-cells are the natural target cells of HIV-1 infection. A consensus has not been reached as to whether HIV replication result...

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Detalles Bibliográficos
Autores principales: Cromer, Deborah, Schlub, Timothy E., Smyth, Redmond P., Grimm, Andrew J., Chopra, Abha, Mallal, Simon, Davenport, Miles P., Mak, Johnson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848610/
https://www.ncbi.nlm.nih.gov/pubmed/27110814
http://dx.doi.org/10.3390/v8040118