The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation

Clostridium sordellii lethal toxin (TcsL) is a powerful virulence factor responsible for severe toxic shock in man and animals. TcsL belongs to the large clostridial glucosylating toxin (LCGT) family which inactivates small GTPases by glucosylation with uridine-diphosphate (UDP)-glucose as a cofacto...

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Detalles Bibliográficos
Autores principales: Varela Chavez, Carolina, Haustant, Georges Michel, Baron, Bruno, England, Patrick, Chenal, Alexandre, Pauillac, Serge, Blondel, Arnaud, Popoff, Michel-Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848617/
https://www.ncbi.nlm.nih.gov/pubmed/27023605
http://dx.doi.org/10.3390/toxins8040090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848617/
https://www.ncbi.nlm.nih.gov/pubmed/27023605
http://dx.doi.org/10.3390/toxins8040090

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