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δ-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats

PnTx4(6-1), henceforth renamed δ-Ctenitoxin-Pn1a (δ-CNTX-Pn1a), a peptide from Phoneutria nigriventer spider venom, initially described as an insect toxin, binds to site 3 of sodium channels in nerve cord synaptosomes and slows down sodium current inactivation in isolated axons in cockroaches (Perip...

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Detalles Bibliográficos
Autores principales: Emerich, Bruna Luiza, Ferreira, Renata C. M., Cordeiro, Marta N., Borges, Márcia Helena, Pimenta, Adriano M. C., Figueiredo, Suely G., Duarte, Igor Dimitri G., de Lima, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848632/
https://www.ncbi.nlm.nih.gov/pubmed/27077886
http://dx.doi.org/10.3390/toxins8040106