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The Scorpion Toxin Analogue BmKTX-D33H as a Potential Kv1.3 Channel-Selective Immunomodulator for Autoimmune Diseases

The Kv1.3 channel-acting scorpion toxins usually adopt the conserved anti-parallel β-sheet domain as the binding interface, but it remains challenging to discover some highly selective Kv1.3 channel-acting toxins. In this work, we investigated the pharmacological profile of the Kv1.3 channel-acting...

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Detalles Bibliográficos
Autores principales: Ye, Fang, Hu, Youtian, Yu, Weiwei, Xie, Zili, Hu, Jun, Cao, Zhijian, Li, Wenxin, Wu, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848641/
https://www.ncbi.nlm.nih.gov/pubmed/27104568
http://dx.doi.org/10.3390/toxins8040115