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Pharmacological inhibition of I(K) (1) by PA‐6 in isolated rat hearts affects ventricular repolarization and refractoriness

The inwardly rectifying potassium current (I(K) (1)) conducted through K(ir)2.X channels contribute to repolarization of the cardiac action potential and to stabilization of the resting membrane potential in cardiomyocytes. Our aim was to investigate the effect of the recently discovered I(K) (1) in...

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Detalles Bibliográficos
Autores principales: Skarsfeldt, Mark A., Carstensen, Helena, Skibsbye, Lasse, Tang, Chuyi, Buhl, Rikke, Bentzen, Bo H., Jespersen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848716/
https://www.ncbi.nlm.nih.gov/pubmed/27117805
http://dx.doi.org/10.14814/phy2.12734