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Maternal corticosterone exposure in the mouse programs sex‐specific renal adaptations in the renin–angiotensin–aldosterone system in 6‐month offspring

Short‐term maternal corticosterone (Cort) administration at mid‐gestation in the mouse reduces nephron number in both sexes while programming renal and cardiovascular dysfunction in 12‐month male but not female offspring. The renal renin–angiotensin–aldosterone system (RAAS), functions in a sexually...

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Detalles Bibliográficos
Autores principales: Cuffe, James S. M., Burgess, Danielle J., O'Sullivan, Lee, Singh, Reetu R., Moritz, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848720/
https://www.ncbi.nlm.nih.gov/pubmed/27122048
http://dx.doi.org/10.14814/phy2.12754