Cargando…

TNF/Ang‐II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function

Angiotensin‐II (Ang‐II) infusion is associated with the development of interstitial fibrosis in both heart and kidney as a result of chemokine‐dependent uptake of monocytes and subsequent development of myeloid fibroblasts. This study emphasizes on the synergistic role of tumor necrosis factor (TNF)...

Descripción completa

Detalles Bibliográficos
Autores principales: Mayr, Magdalena, Duerrschmid, Clemens, Medrano, Guillermo, Taffet, George E., Wang, Yanlin, Entman, Mark L., Haudek, Sandra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848723/
https://www.ncbi.nlm.nih.gov/pubmed/27125666
http://dx.doi.org/10.14814/phy2.12765