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TNF/Ang‐II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function
Angiotensin‐II (Ang‐II) infusion is associated with the development of interstitial fibrosis in both heart and kidney as a result of chemokine‐dependent uptake of monocytes and subsequent development of myeloid fibroblasts. This study emphasizes on the synergistic role of tumor necrosis factor (TNF)...
Autores principales: | Mayr, Magdalena, Duerrschmid, Clemens, Medrano, Guillermo, Taffet, George E., Wang, Yanlin, Entman, Mark L., Haudek, Sandra B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848723/ https://www.ncbi.nlm.nih.gov/pubmed/27125666 http://dx.doi.org/10.14814/phy2.12765 |
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