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Down-regulation of p21-activated serine/threonine kinase 1 is involved in loss of mesencephalic dopamine neurons

BACKGROUND: Although the roles of p21-activated serine/threonine kinase 1 (PAK1) have been reported in some neurodegenerative diseases, details regarding neurodegeneration are still limited. Hence, we tried to determine the role of PAK1 and molecular mechanisms of neuronal death involved in neurodeg...

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Detalles Bibliográficos
Autores principales: Kim, Hwanhee, Oh, Jun-Young, Choi, Sun-Lim, Nam, Yeon-Ju, Jo, Anna, Kwon, Ara, Shin, Eun-Young, Kim, Eung-Gook, Kim, Hyong Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848805/
https://www.ncbi.nlm.nih.gov/pubmed/27121078
http://dx.doi.org/10.1186/s13041-016-0230-6