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ImiRP: a computational approach to microRNA target site mutation

BACKGROUND: MicroRNAs (miRNAs) are small ~22 nucleotide non-coding RNAs that function as post-transcriptional regulators of messenger RNA (mRNA) through base-pairing to 6–8 nucleotide long target sites, usually located within the mRNA 3’ untranslated region. A common approach to validate and probe m...

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Detalles Bibliográficos
Autores principales: Ryan, Bridget C., Werner, Torben S., Howard, Perry L., Chow, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848830/
https://www.ncbi.nlm.nih.gov/pubmed/27122020
http://dx.doi.org/10.1186/s12859-016-1057-y