Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy

BACKGROUND: Trimetazidine, as an anti-ischemic and antioxidant agent, has been demonstrated to have many cardioprotective effects. However, whether early administration of trimetazidine has an effect on diabetic cardiomyopathy and the mechanisms underlying the effect have not yet been elucidated. ME...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Ding, Wen-yuan, Wang, Zhi-hao, Tang, Meng-xiong, Wang, Feng, Li, Ya, Zhong, Ming, Zhang, Yun, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848862/
https://www.ncbi.nlm.nih.gov/pubmed/27121077
http://dx.doi.org/10.1186/s12967-016-0849-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848862/
https://www.ncbi.nlm.nih.gov/pubmed/27121077
http://dx.doi.org/10.1186/s12967-016-0849-1

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