Mechanical and IL-1β Responsive miR-365 Contributes to Osteoarthritis Development by Targeting Histone Deacetylase 4

Mechanical stress plays an important role in the initiation and progression of osteoarthritis. Studies show that excessive mechanical stress can directly damage the cartilage extracellular matrix and shift the balance in chondrocytes to favor catabolic activity over anabolism. However, the underlyin...

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Detalles Bibliográficos
Autores principales: Yang, Xu, Guan, Yingjie, Tian, Shaoqi, Wang, Yuanhe, Sun, Kang, Chen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848892/
https://www.ncbi.nlm.nih.gov/pubmed/27023516
http://dx.doi.org/10.3390/ijms17040436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848892/
https://www.ncbi.nlm.nih.gov/pubmed/27023516
http://dx.doi.org/10.3390/ijms17040436

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