The Autophagic Process Occurs in Human Bone Metastasis and Implicates Molecular Mechanisms Differently Affected by Rab5a in the Early and Late Stages

Autophagy favours metastatic growth through fuelling energy and nutrients and resistance to anoikis, typical of disseminated-tumour cells. The autophagic process, mediated by a unique organelle, the autophagosome, which fuses with lysosomes, is divided into three steps. Several stages, especially ea...

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Detalles Bibliográficos
Autores principales: Maroni, Paola, Bendinelli, Paola, Resnati, Massimo, Matteucci, Emanuela, Milan, Enrico, Desiderio, Maria Alfonsina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848899/
https://www.ncbi.nlm.nih.gov/pubmed/27023526
http://dx.doi.org/10.3390/ijms17040443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848899/
https://www.ncbi.nlm.nih.gov/pubmed/27023526
http://dx.doi.org/10.3390/ijms17040443

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